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NXT1 Mouse mAb
NXT1 Mouse mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, ICC |
|---|---|
| Primary Accession | Q9UKK6 |
| Reactivity | Rat, Human, Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Calculated MW | 15 KDa |
| Physical State | Liquid |
| Immunogen | Recombinant human NXT1 protein |
| Isotype | IgG2a |
| Purity | affinity purified by Protein G |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. |
| SIMILARITY | Contains 1 NTF2 domain. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Gene ID | 29107 |
|---|---|
| Other Names | NTF2-related export protein 1, Protein p15, NXT1 |
| Dilution | WB=1:5000-20000,ICC/IF=1:100-400 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | NXT1 |
|---|---|
| Function | Stimulator of protein export for NES-containing proteins (PubMed:10567585). Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA (PubMed:10848583). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 (PubMed:11259602, PubMed:19165146). |
| Cellular Location | Nucleus. Nucleus speckle. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm |
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Provided below are standard protocols that you may find useful for product applications.
Background
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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